Glgc gwas

Author: jwgt

August undefined, 2024

WebFeb 6, 2024 · Valuable information is available on this page for local and tribal health departments (LHD) regarding the overall contracting process and LHD allocations. The … WebNov 13, 2024 · We used summary statistics from a genome-wide association study (GWAS) that included 441,016 participants from the UK Biobank as the exposure dataset of lipid-related traits and from COVID-19 Host Genetics Initiative GWAS meta-analyses of European ancestry as the outcome dataset for COVID-19 susceptibility (32,494 cases …

Genetically regulated gene expression underlies lipid traits in

WebOct 26, 2024 · Additional information regarding the GWAS data (consortium, study cohort, and author information of the GWAS for the exposure and neuropsychiatric outcomes) are located in Table S1. We performed cis ‐instrumentation of genetically predisposed PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibition in several complementary data sets. WebResults: PheGWAS is demonstrated using summary data from Global Lipids Genetics Consortium (GLGC) GWAS across multiple lipid traits. For single and multiple traits PheGWAS highlighted all... init byte array c

Example of a LocusTrack plot. The plot shows regional GWAS …

WebOct 30, 2024 · The in silico replication study was conducted with data from additional independent individuals of European ancestry from the Nord-Trøndelag Health Study (HUNT) 19 and GLGC GWAS 2, and Chinese ... WebStaff Directory Members By Category/Department; Name Title Email Address Phone; Jeremy Sheetinger: Head Coach [email protected]: 678-407-5761 678-407-5761: Evan … http://csg.sph.umich.edu/willer/public/glgc-lipids2024/ init byte array java

Network-based Analysis of Genome Wide Association Data …

PheGWAS: A new dimension to visualize GWAS across …

WebSep 27, 2024 · The first step of this study was to pick out m 6 A-SNPs from the GLGC GWAS data set which contained 2.6 million SNPs according to the annotation information of the 313,000 m 6 A-SNPs in the... WebJun 5, 2024 · The GLGC data set includes ~300,000 individuals of primarily European ancestry genotyped with the HumanExome BeadChip (exome array) 33. The participants were from 73 different studies and... initcallbackWebNov 4, 2016 · For GWAS, linkage disequilibrium is a source of confounding marker dependencies. MSEA was less sensitive to LD thresholds for better powered studies such as the GLGC GWAS but smaller studies benefited from less stringent LD cutoffs, presumably due to improved statistical power (Additional file 2: Figure S1). initcall_async

"WebJun 30, 2024 · The replication rates are high for all four methods: among the significant genes identified in the GLGC GWAS, 161 out of 200 (81%), 79 out of 108 (73%), 93 out of 120 (77%), and 52 out of 69 (75%) were … " - Glgc gwas

Glgc gwas

Frontiers Association of the gut microbiota with coronary artery ...

WebMar 31, 2024 · Recommended steps. GSA can assist you by offering free scope compatibility reviews for all GWACs and capabilities statement requests for small … WebNov 13, 2024 · Upload and share GWAS results with my.locuszoom.org ~ October 14, 2024 We are happy to announce the newest stage in our efforts to support interactive, exploratory GWAS plots: the new my.locuszoom.org upload-to-plot service. This new service generates fully interactive plots, with no limits on the number of loci you can explore.

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WebGlobal Lipids Genetics Consortium (GLGC) Low Density Lipoprotein Cholesterol Willer (2013) 96% European ancestry ieu-a-300 mg/dl Coronary Artery Disease CARDIoGRAMplusC4D ... #NAFLD GWAS Dataset by Graham et al. (discovery dataset). Power (NAFLDǂ) ǂ NAFLD GWAS Dataset by Anstee et al. (replication dataset). 0.656 … WebThe Global Lipids Genetics Consortium aggregated GWAS results from 1,654,960 individuals from 201 primary studies representing five genetic ancestry groups: Admixed …

WebApr 27, 2024 · We also evaluated the effects of lipid concentrations on AAD. Summary statistics from the Global Lipids Genetics Consortium (GLGC) GWAS, which identified more than one hundred lipid-associated loci, were applied in the present study (42, 43). The “high cholesterol” GWAS included 55,265 cases and 396,999 controls. The “Disorders of ... http://pharmafocusasia.com/researchinsights/the-relationship-between-circulating-lipids-and-breast-cancer-risk

Web6 fetchContentEbi Examples gencodeGeneInfo <- extractGeneInfo(gencodeGeneInfoAllGranges) fetchContent Fetch data using url by three methods Description WebMar 29, 2024 · Fifth, the GLGC GWAS used to select instruments for plasma TG levels in discovery had accounted for lipid-lowering treatment, while the UKB GWAS used in replication had not. Last, we acknowledge that this study was restricted to populations of European ancestry, limiting the generalizability of our findings.

WebJul 8, 2024 · Results: PheGWAS is demonstrated using data from Global Lipids Gene tics Consortium (GLGC) GWAS across multiple lipid traits. For single trait matching, PheGWAS highlighted all eighty -eight loci, seventy-two genes and sixty-three SNPs matched in the GLGC data. For multiple trait matching, sixty -eight of sixty-nine loci were detected,

WebThe NHGRI-EBI GWAS Catalog: a curated collection of all published genome-wide association studies, produced by a collaboration between EMBL-EBI and NHGRI. Toggle … init byWebJun 30, 2024 · Results of the LDL-C analysis using the GLGC GWAS summary statistics. A) Bar plots of the number of significant genes using different methods; B) Venn diagram … init c# 9http://csg.sph.umich.edu/willer/public/lipids2013/ init by luaWebUsing GWAS and comorbidity data, we present a network-based approach to predict candidate genes for lipid and lipoprotein traits. We apply a prediction pipeline … init bytearray kotlinWebJun 17, 2024 · Extended Data Fig. 7 shows the number of Bonferroni-significant SNPs overlapping between lipid GWAS (eMERGE, GERA, GLGC and UKB) and lipid-guided PheWAS (eMERGE and UKB). initcachehttp://locuszoom.sph.umich.edu/ initcall_blacklist hisi_ddrc_pmu_module_initWebVariant set derived from blood-lipid GWAS results from GLGC and HUNT consortium Integrated transcript- and variant-level functional annotations via Ensembl Variant Effect Predictor init cadwork