WebShufeiya Recipe Improves Monocrotaline-Induced Pulmonary Hypertension in Rats by Regulating SIRT3/FOXO3a and Its Downstream Signaling Pathways Figure 1 Shufeiya Recipe significantly relieved mPAP and pathological changes of lung tissue of PH rats. WebDec 28, 2024 · Results: Shufeiya recipe contained 67 active components. 61 common proteins of the target proteins of the active components and PH-related core proteins were obtained. The treatment involved both ...
Shufeiya Recipe Improves Monocrotaline-Induced Pulmonary …
Objective. This study is aimed at exploring the molecular mechanism of Shufeiya recipe in the treatment of pulmonary hypertension (PH) using network pharmacology and molecular docking analysis. Methods. Active components and their target proteins in the recipe were screened using the TCMSP … See more Pulmonary hypertension (PH) is a chronic progressive pulmonary vascular system disease caused by pulmonary arteriole obstruction, and it is characterized by pulmonary artery … See more A total of 67 active components of Shufeiya recipe were obtained from the TCMSP database, including 3 active components from platycodi radix, 52 active components from Salvia miltiorrhiza, 10 active … See more Based on the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) (http://tcmspw.com/tcmsp.php) [ 1. J. Ru, P. Li, J. Wang et al., “TCMSP: a database of systems … See more The occurrence of PH is closely related to abnormalities in the pulmonary vascular function and/or structure. Long-term hypoxia or other factors damage the endothelial cell … See more WebDownload scientific diagram Shufeiya Recipe upregulated concentration of NO, sGC, and cGMP and the protein expression level of PKG in PH rats. (a) Moderate and high groups of Shufeiya Recipe ... motorcycle warning light cluster
Network Pharmacology and Molecular Docking Analysis of …
WebFeb 18, 2024 · The traditional Chinese medicine (TCM) compound "Shufeiya Recipe" was used to intervene in monocrotaline- (MCT-) induced pulmonary hypertension in rats. The rats were randomly divided into the control group, model group, positive drug (Sildenafil) … WebShufeiya Recipe upregulated concentration of NO, sGC, and cGMP and the protein expression level of PKG in PH rats. (a) Moderate and high groups of Shufeiya Recipe upregulated the protein expression level of PKG, . Web2024 Jun 1 Department of Epidemiology and Health Statistics, School of Public Health, Hebei Medical University, China Abnormal fasting blood glucose enhances the risk of long-term exposure to air pollution on dyslipidemia motorcycle warranty